What is Alzheimer and what goes wrong in brain?

  • More than 100 years ago, Dr. Alois Alzheimer described specific changes in the brain that are now known as beta-amyloid plaques and tau tangles.
  • Today we know that Alzheimer’s is a progressive brain disease that’s marked by these key changes and thought to impact memory, thinking and behavior.
  • Now let us understand- What goes wrong in the brain
  • The brain has three main parts: the cerebrum, cerebellum and brain stem. Each one plays a role in how the body functions.
  • The cerebrum fills up most of the skull. It’s the part of the brain most involved in remembering, problem-solving and thinking.
  • There are about 100 billion nerve cells (neurons) throughout the brain that transmit messages in order for us to create memories, feelings and thoughts.
  • Alzheimer’s disease causes nerve cells to die, which leads to brain tissue loss, or shrinkage,and causes loss of function and communication between cells.
  • These changes can cause the symptoms of Alzheimer’s disease, such as memory loss; problems with thinking and planning; behavioral issues; and, in the last stage, a further decline in functioning, difficulty swallowing.

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